Stem Cells in Cancer: Should We Believe or Not?

This volume explores the latest developments in a novel area of molecular biology and a hot topic in the field of oncology: cancer stem cells. These chapters from expert contributing authors present concepts such as the universal stem cell, new molecular pathways, new targeted agents, the different...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Grande, Enrique (Επιμελητής έκδοσης), Antón Aparicio, Luis (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Dordrecht : Springer Netherlands : Imprint: Springer, 2014.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
LEADER 03684nam a22004695i 4500
001 978-94-017-8754-3
003 DE-He213
005 20151125222257.0
007 cr nn 008mamaa
008 140428s2014 ne | s |||| 0|eng d
020 |a 9789401787543  |9 978-94-017-8754-3 
024 7 |a 10.1007/978-94-017-8754-3  |2 doi 
040 |d GrThAP 
050 4 |a RC261-271 
072 7 |a MJCL  |2 bicssc 
072 7 |a MED062000  |2 bisacsh 
082 0 4 |a 614.5999  |2 23 
245 1 0 |a Stem Cells in Cancer: Should We Believe or Not?  |h [electronic resource] /  |c edited by Enrique Grande, Luis Antón Aparicio. 
264 1 |a Dordrecht :  |b Springer Netherlands :  |b Imprint: Springer,  |c 2014. 
300 |a VIII, 299 p. 23 illus., 19 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
505 0 |a Foreword -- The universal stem cell: does it exist? -- What is the meaning of Notch pathway and how we can selectively do the targeting -- Hedhehog as a new paradigm in cancer treatment Stem cells in cancer: should we believe or not? -- Wnt pathway at a glance: from the deep of the crypts to the current ways of targeting -- Cancer Stem Cells in Brest Cancer --  Cancer Stem Cells in Colon Cancer -- Cancer Stem Cells in Genitourinary Cancer -- Cancer Stem Cells in Pancreatic Cancer -- Cancer Stem Cells in Gastric Cancer -- Cancer Stem Cells in Melanoma -- Cancer Stem Cells in Brain Tumors -- Cancer Stem Cells in Sarcomas -- Cancer Stem Cells in Gynecologic Tumors. 
520 |a This volume explores the latest developments in a novel area of molecular biology and a hot topic in the field of oncology: cancer stem cells. These chapters from expert contributing authors present concepts such as the universal stem cell, new molecular pathways, new targeted agents, the different roles that cancer stem cells seem to have according to the organ they are placed in, and the future role that targeting cancer stem cells may have in the management of patients in the clinic.    Exploring the latest research including new data from randomized trials, this book examines important proposals over the origin of cancer stem cells such as the possibility that cancer stem cells may arise from mutated stem cells or a fully differentiated cell that may undergo several mutations that drive it back to a stem-like state. The authors consider the role that stem cells seem to have in the onset, development and resistance to classical antitumoral treatments of cancer and discuss possible potential future treatment modalities for the management of advanced cancer patients.  The question, "Are stem cells involved in cancer?" may not have a simple answer, but ongoing investigations, in-depth consideration and a broad spectrum of information can be found in this book, allowing the reader to arrive at his or her own answer.   This book will appeal to researchers in the field of oncology and cancer research and biomedical scientists with an interest in stem cells. 
650 0 |a Medicine. 
650 0 |a Cancer research. 
650 0 |a Oncology. 
650 0 |a Stem cells. 
650 1 4 |a Biomedicine. 
650 2 4 |a Cancer Research. 
650 2 4 |a Stem Cells. 
650 2 4 |a Oncology. 
700 1 |a Grande, Enrique.  |e editor. 
700 1 |a Antón Aparicio, Luis.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
776 0 8 |i Printed edition:  |z 9789401787536 
856 4 0 |u http://dx.doi.org/10.1007/978-94-017-8754-3  |z Full Text via HEAL-Link 
912 |a ZDB-2-SBL 
950 |a Biomedical and Life Sciences (Springer-11642)