I Domain Integrins

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Gullberg, Donald (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Dordrecht : Springer Netherlands : Imprint: Springer, 2014.
• Σειρά: Advances in Experimental Medicine and Biology, 819
• Θέματα: Medicine.; Medical genetics.; Medical biochemistry.; Life sciences.; Biomedicine.; Biomedicine general.; Life Sciences, general.; Gene Function.; Medical Biochemistry.

The integrin family is composed of 24 members and approximately ten years ago (2003) we published a book devoted to the nine I domain integrin subunits. In this second edition, I am pleased that most of the original authors have been able to contribute to the updated version. I domain containing int...

Πίνακας περιεχομένων:

• Preface
• 1 Evolution of integrin I domains
• 2 Integrin a1b1
• 3 Integrin a2b1
• 4 Integrin a10b1- a collagen receptor critical in skeletal development
• 5 Integrin a11b1 – a major collagen receptor on fibroblastic cells
• 6 Regulation of integrin activity by phosphorylation
• 7 Integrin aEb7:molecular features and functional significance in the immune system
• 8 Structural aspects of integrins
• 9 Integrin recognition motifs in the human collagens
• 10 Cellular signalling by collagen-binding integrins
• 11 The therapeutic potential of I-domain integrins
• Index.