Circulating Nucleic Acids in Early Diagnosis, Prognosis and Treatment Monitoring An Introduction /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Gahan, Peter B. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Dordrecht : Springer Netherlands : Imprint: Springer, 2015.
• Σειρά: Advances in Predictive, Preventive and Personalised Medicine, 5
• Θέματα: Medicine.; Cancer research.; Medicinal chemistry.; Health promotion.; Nucleic acids.; Biomedicine.; Biomedicine general.; Health Promotion and Disease Prevention.; Cancer Research.; Nucleic Acid Chemistry.; Medicinal Chemistry.

DNA and RNA fractions can be isolated from a variety of body fluids including whole blood, serum, plasma, urine, saliva and cerebrospinal fluid from both patients and healthy individuals.  Such isolates can be exploited in the early detection of clinical disorders, stratification of patients for tre...

Πίνακας περιεχομένων:

• Part I. BACKGROUND
• CHAPTER 1 Introduction - Brief History and the present and future status of CNAPS
• CHAPTER 2 The biology of CNAPS
• Part II. METHODOLOGY
• CHAPTER 3 Pre-analytical requirements for analysing nucleic acids from blood
• CHAPTER 4. Circulating DNA and miRNA isolation
• CHAPTER 5 Detection of genetic alterations by nucleic acid analysis: use of pcr and mass spectroscopy-based methods
• CHAPTER 6 Genomic approaches to the analysis of cell free nucleic acids
• Part III APPLICATIONS
• CHAPTER 7 CNAPS and General Medicine
• CHAPTER 8 Fetal CNAPS – DNA/RNA
• CHAPTER 9 Circulating nucleic acids and Diabetes mellitus
• CHAPTER 10 Extracellular nucleic acids and cancer
• CHAPTER 11 Other bodily fluids as non-invasive sources of Cell-free DNA/RNA
• CHAPTER 12 CNAPS in therapy monitoring
• Part IV OTHER ASPECTCS
• CHAPTER 13 Quality Assurance
• CHAPTER 14 Societal Aspects: Ethics.