From Protein Structure to Function with Bioinformatics

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: J. Rigden, Daniel (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Dordrecht : Springer Netherlands : Imprint: Springer, 2017.
• Έκδοση: 2nd ed. 2017.
• Θέματα: Life sciences.; Proteomics.; Proteins.; Bioinformatics.; Computational biology.; Life Sciences.; Protein Science.; Biomedicine general.; Computer Appl. in Life Sciences.

This book is about protein structural bioinformatics and how it can help understand and predict protein function. It covers structure-based methods that can assign and explain protein function based on overall folds, characteristics of protein surfaces, occurrence of small 3D motifs, protein-protein...

Πίνακας περιεχομένων:

• Preface
• Ab Initio Protein Structure Prediction
• Protein structures, interactions and function from evolutionary couplings.-Fold Recognition
• Comparative protein structure modelling
• Advances in computational methods for transmembrane protein structure prediction
• Bioinformatics approaches to the structure and function of intrinsically disordered proteins
• Prediction of Protein Aggregation and Amyloid Formation
• Prediction of biomolecular complexes
• Function Diversity within Folds and Superfamilies
• Function prediction using patches, pockets and other surface properties
• 3D Motifs
• Protein Dynamics: From Structure to Function
• Integrated servers for structure-informed function prediction
• Case Studies: Function Predictions Of Structural Genomics Results
• Prediction of protein function from theoretical models
• Index.