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03517nam a22004575i 4500 |
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978-981-10-1498-7 |
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DE-He213 |
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20160704101535.0 |
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cr nn 008mamaa |
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160704s2016 si | s |||| 0|eng d |
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|a 9789811014987
|9 978-981-10-1498-7
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7 |
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|a 10.1007/978-981-10-1498-7
|2 doi
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|d GrThAP
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|a RC261-271
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|a MJCL
|2 bicssc
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|a MED062000
|2 bisacsh
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|a 614.5999
|2 23
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| 245 |
1 |
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|a The Long and Short Non-coding RNAs in Cancer Biology
|h [electronic resource] /
|c edited by Erwei Song.
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| 264 |
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1 |
|a Singapore :
|b Springer Singapore :
|b Imprint: Springer,
|c 2016.
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| 300 |
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|a VIII, 458 p. 21 illus.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a text file
|b PDF
|2 rda
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| 490 |
1 |
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|a Advances in Experimental Medicine and Biology,
|x 0065-2598 ;
|v 927
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| 505 |
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|a Non-coding RNAs: New Players in Cancers -- The Working Modules of Long Non-coding RNAs in Cancer Cells -- Methods to Study Long Non-coding RNA Biology in Cancer -- Relationship between Non-coding RNA Dysregulation and Epigenetic Mechanisms in Cancer -- Non-coding RNAs in Growth and Death of Cancer Cells -- Non-coding RNAs in Cancer Cell Plasticity -- Non-coding RNAs in Regulation of Cancer Metabolic Reprogramming -- Non-coding RNAs in Tumor Angiogenesis -- Non-coding RNAs in Cancer Immunity -- Non-coding RNAs in Therapeutic Resistance of Cancer -- Non-coding RNAs Regulating Cancer Signaling Network -- Non-coding RNAs Regulating NFkB Signaling -- Non-coding RNAs Regulating p53 and c-Myc Signaling -- Viral Non-coding RNAs in Cancer Biology -- Non-coding RNAs in Cancer Diagnosis -- Therapeutic Potentials of Non-coding RNAs: Targeted Delivery of NcRNAs in Cancer Cells.
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| 520 |
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|a The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.
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| 650 |
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0 |
|a Medicine.
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| 650 |
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|a Cancer research.
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| 650 |
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|a Cell biology.
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| 650 |
1 |
4 |
|a Biomedicine.
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| 650 |
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4 |
|a Cancer Research.
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| 650 |
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4 |
|a Cell Biology.
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| 700 |
1 |
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|a Song, Erwei.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 776 |
0 |
8 |
|i Printed edition:
|z 9789811014963
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| 830 |
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0 |
|a Advances in Experimental Medicine and Biology,
|x 0065-2598 ;
|v 927
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| 856 |
4 |
0 |
|u http://dx.doi.org/10.1007/978-981-10-1498-7
|z Full Text via HEAL-Link
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| 912 |
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
|
