Cystogenesis

• Corporate Author: SpringerLink (Online service)
• Other Authors: Park, Jong Hoon (Editor), Ahn, Curie (Editor)
• Format: Electronic eBook
• Language: English
• Published: Singapore : Springer Singapore : Imprint: Springer, 2016.
• Series: Advances in Experimental Medicine and Biology, 933
• Subjects: Medicine.; Human genetics.; Medical microbiology.; Molecular biology.; Cell biology.; Biomedicine.; Human Genetics.; Molecular Medicine.; Cell Biology.; Medical Microbiology.

This book covers the mechanisms of renal cyst development as well as the aberrant signaling pathways which are involved in Autosomal Dominant Polycystic Kidney Disease (ADPKD). ADPKD is a genetic disease in which cysts appear in the epithelial lining of both kidneys. End stage ADPKD patients experie...

Table of Contents:

• Part I ADPKD Overview
• Chapter 1 Recent Trends in ADPKD Research
• Chapter 2 Genetic Mechanisms of ADPKD
• Part II Cystogenesis Mechanisms
• Chapter 3 Cell Proliferation and Apoptosis in ADPKD
• Chapter 4 Inflammation and Fibrosis in ADPKD
• Chapter 5 Functional Study of the Primary Cilia in ADPKD
• Chapter 6 Epigenetic Regulation in Cystogenesis
• Part III Therapeutic Approaches and Diagnostic Markers for ADPKD
• Chapter 7 Validation of Effective Therapeutic Targets for ADPKD using Animal Models
• Chapter 8 Diagnostic Evaluation as a Biomarker in Patients with ADPKD
• Chapter 9 Clinical Trials and a View toward the Future of ADPKD.