New Strategies for N-Heterocyclic Carbenes Catalyzed Annulations

• Main Author: Chen, Xiangyu (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Singapore : Springer Singapore : Imprint: Springer, 2017.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Chemistry.; Organic chemistry.; Medicinal chemistry.; Catalysis.; Organic Chemistry.; Medicinal Chemistry.

This thesis focuses on NHC-catalyzed annulation of nitroalkenes, enals and α,β-unsaturated carboxylic acids. (1) NHCs were found to be efficient catalysts for the [4+2] annulation of β-substituted nitroalkenes. The scope of Rauhut–Currier reaction was successfully extended to the most challenging β-...

Table of Contents:

• Introduction
• NHC-catalyzed Annulations of Nitroalkenes
• NHC-catalyzed Enantioselective Annulations of Enals
• NHC-catalyzed Enantioselective Annulations of α,β-unsaturated Carboxylic Acids
• Experimental Part
• Research Summary.