New Carbon–Carbon Coupling Reactions Based on Decarboxylation and Iron-Catalyzed C–H Activation

• Main Author: Shang, Rui (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Singapore : Springer Singapore : Imprint: Springer, 2017.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Chemistry.; Organometallic chemistry.; Chemistry, Physical and theoretical.; Catalysis.; Organometallic Chemistry.; Theoretical and Computational Chemistry.

This thesis presents the latest developments in new catalytic C–C bond formation methods using easily accessible carboxylate salts through catalytic decarboxylation with good atom economy, and employing the sustainable element iron as the catalyst to directly activate C–H bonds with high step effici...

Table of Contents:

• Introduction to Carbon-Carbon Coupling Reactions Based on Decarboxylation and Iron-Catalyzed C-H Activation
• Part I New Carbon-Carbon Bond Formation Methodologies Based on Decarboxylation
• Transition-Metal-Catalyzed Decarboxylation and Decarboxylative Cross-Couplings
• Palladium-Catalyzed Decarboxylative Coupling of Potassium Oxalate Monoester with Aryl and Alkenyl Halides
• Synthesis of Polyfluorobiaryls via Copper-Catalyzed Decarboxylative Couplings of Potassium Polyfluorobenzoates with Aryl Bromides and Iodides
• Palladium-Catalyzed Decarboxylative Couplings of Potassium Polyfluorobenzoates with Aryl Bromides, Chlorides and Triflates
• Construction of C(sp3)-C(sp2) Bonds via Palladium-Catalyzed Decarboxylative Couplings of 2-(2-Azaaryl)acetate Salts with Aryl Halides
• Synthesis of α-Aryl Nitriles and α-Aryl Acetate Esters via Palladium-Catalyzed Decarboxylative Couplings of α-Cyano Carboxylate Salts and Malonate Monoester Salts with Aryl Halides
• Palladium-Catalyzed Decarboxylative Couplings of Nitrophenyl Acetate Salts and Its Derivatives with Aryl Halides
• Palladium-Catalyzed Decarboxylative Benzylation of α-Cyano Aliphatic Carboxylate Salts with Benzyl Electrophiles
• Part II New Carbon-Carbon Bond Formation Methodologies Based on Iron-Catalyzed C-H Activation
• Recent Develpments of Iron-Catalyzed Directed C-H Activation/C-C Bond Formation Reactions.-β-Arylation of Carboxamides via Iron-Catalyzed C(sp3)–H Bond Activation
• Iron-Catalyzed C(sp2)–H and C(sp3)–H Bond Functionalization with Organoboron Compounds.