Organelle Contact Sites From Molecular Mechanism to Disease /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Tagaya, Mitsuo (Επιμελητής έκδοσης), Simmen, Thomas (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2017.
• Σειρά: Advances in Experimental Medicine and Biology, 997
• Θέματα: Life sciences.; Cancer research.; Human physiology.; Immunology.; Molecular biology.; Biochemistry.; Cell biology.; Life Sciences.; Cell Biology.; Biochemistry, general.; Molecular Medicine.; Human Physiology.; Cancer Research.

This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases. MCS, the intracellular structures where organellar membranes...

Πίνακας περιεχομένων:

• Part 1: Overview of Organelle Contacts
• Chapter 1: Organelle Communication at Membrane Contact Sites (MCS): From Curiosity to Center Stage in Cell Biology and Biomedical Research
• Part 2: Organization and Roles of Organelle Contact Sites
• Chapter 2: Over Six Decades of Discovery and Characterization of the Architecture at Mitochondria-Associated Membranes (MAMs)
• Chapter 3: Regulation of mitochondrial dynamics and autophagy by the mitochondria-associated membrane
• Chapter 4: Endoplasmic Reticulum-Mitochondria Communication Through Ca2+ signaling: the importance of mitochondria associated membranes (MAMs)
• Chapter 5: Ceramide transport from the endoplasmic reticulum to the trans Golgi region at organelle membrane contact sites
• Chapter 6: Endoplasmic Reticulum - Plasma Membrane cross-talk mediated by the extended synaptotagmins
• Chapter 7: Endoplasmic Reticulum–Plasma membrane contacts regulate cellular excitability
• Chapter 8: The lipid droplet and the endoplasmic reticulum
• Chapter 9: Role of intra- and inter-mitochondrial membrane contact sites in yeast phospholipid biogenesis
• Chapter 10: Discovery and roles of ER-endolysosomal contact sites in disease
• Part 3: Infection and Disease
• Chapter 11: Alzheimer disease
• Chapter 12: Mitochondrial-associated membranes in Parkinson’s disease
• Chapter 13: Role of endoplasmic reticulum-mitochondria communication in type 2 diabetes
• Chapter 14: Mitochondria–endoplasmic reticulum contact sites mediate innate immune responses
• Chapter 15: Hepatitis C Virus Replication
• Chapter 16: Hijacking of Membrane Contact Sites by Intracellular Bacterial Pathogens
• Chapter 17: Alterations in Ca2+ signalling via ER-mitochondria contact site remodelling in cancer.