Developmental Origins of Health and Disease (DOHaD) From Biological Basis to Clinical Significance /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Kubota, Takeo (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Fukuoka, Hideoki (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2018.
• Έκδοση: 1st ed. 2018.
• Σειρά: Advances in Experimental Medicine and Biology, 1012
• Θέματα: Human physiology.; Reproductive medicine.; Developmental biology.; Human Physiology.; Reproductive Medicine.; Developmental Biology.

This book addresses the developmental origins of health and disease (DOHaD), a new medical concept that demonstrates that various adult diseases start in the fetal period. It discusses our current understanding of the molecular mechanisms of DOHaD, including gene body epigenetics and non-coding RNA,...

Πίνακας περιεχομένων:

• Part 1 Biological Basis
• One carbon metabolism and lipid metabolism in DOHaD
• Novel models of epigenetic gene regulation in the nutritional environment
• Epigenetic switching and neonatal nutritional environment
• Part 2 Disease and environment
• Developmental Origins of Non-Alcoholic Fatty Liver Disease (NAFLD)
• Fetal origins of hypertension
• Involvement of noncoding RNAs in stress-related neuropsychiatric diseases caused by DOCaD theory
• Part 3 Transgenerational mechanism and its consequences
• Placental development and nutritional environment
• Risk of neurodevelopmental disease by paternal aging: a possible influence of epigenetic alteration in sperm
• Part 4 Clinical Significance
• Preemptive epigenetic medicine based on fetal programming.