Pathophysiological Aspects of Proteases

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Chakraborti, Sajal (Επιμελητής έκδοσης), Dhalla, Naranjan S. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2017.
• Θέματα: Medicine.; Cancer research.; Human physiology.; Molecular biology.; Pharmaceutical technology.; Biomedicine.; Human Physiology.; Molecular Medicine.; Pharmaceutical Sciences/Technology.; Cancer Research.

This book provides a comprehensive overview of the multifaceted field of protease in the cellular environment and focuses on the recently elucidated functions of complex proteolytic systems in physiology and pathophysiology. Given the breadth and depth of information covered in the respective contri...

Πίνακας περιεχομένων:

• Protease mediated viral infection
• Role of proteases in cancer pathology especially in breast cancer, as well as role of proteases as posible targets for drug development for cancer
• The multifunctional post-prolinedipeptidyl peptidase, DPP9, in EGF signaling, immunity and cancer biology
• Translating the knowledge of functional dynamics towards designing inhibitors of BACE1, a key aspartate protease in Alzheimer's disease
• Cysteine Dependent Aspartate Specific Proteases in Coronary Artery Disease
• Matrix metalloproteases: Potential role in Type 2 Diabetic Nephropathy
• Matrix-metalloproteinases in Breast Carcinoma, Immunohistology and Prognosis
• Matrix metalloproteinases in parasitic infections
• Role of proteases in cancer metastasis
• Proteolytic activation of kinase growth factors in the pathophysiology of cancer
• Involvement of m-Calpain in Colorectal Adenocarcinomas
• Proteases in Cancer: Potential Therapeutic Targets
• MMPs in Oral Squamous Cell Carcinoma
• Matrix metalloproteinase silencing: a therapeutic approach to treat cardiovascular pathology
• Proteases and Breast cancer
• Matrix metalloproteinases (MMPs) in cancer initiation and progression
• Neutrophil Serine protease in health and disease
• Proteases in disease pathology
• PAR1 mediated apoptosis and tumor regression of breast cancer cells by V. cholerae hemagglutinin protease
• Protein-protease interactions : an overview of the process from an ‘in silico’ perspective
• The functional relevance of Deubiquitinases in life and disease
• Physiological and pathological functions of mitochondrial proteases
• Proteases of parasitic helminths: their metabolic role in establishment of infection in the host
• Cysteine proteases of parasitic helminths
• Targeting proteases in urine for bladder cancer diagnosis.