DJ-1/PARK7 Protein Parkinson’s Disease, Cancer and Oxidative Stress-Induced Diseases /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Ariga, Hiroyoshi (Επιμελητής έκδοσης), Iguchi-Ariga, Sanae M. M. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2017.
• Σειρά: Advances in Experimental Medicine and Biology, 1037
• Θέματα: Medicine.; Cancer research.; Neurosciences.; Biochemistry.; Cell biology.; Biomedicine.; Cancer Research.; Biochemistry, general.; Cell Biology.

This book reviews the functions and roles of DJ-1 in various oxidative stress-related diseases and applications of DJ-1 and its binding compounds to the diseases. The DJ-1 gene was first found to be a novel oncogene in 1997 and later, in 2003, also found to be a causative gene for a familial form of...

Πίνακας περιεχομένων:

• Preface.-　Chapter 1 Introduction/Overview
• Chapter 2 Structural Biology of the DJ-1 Superfamily
• Chapter 3 Expression of DJ-1 in patients with neurodegenerative diseases
• Chapter 4 DJ-1 as an oncogene and its clinical significance
• Chapter 5 Role of DJ-1 in fertilization
• Chapter 6 Anti-oxidative stress function of DJ-1
• Chapter 7 Ttranscriptional regulation of DJ-1
• Chapter 8 Regulation of Signal Transduction by DJ-1
• Chapter 9 Protein repair by DJ-1 from glycation by glyoxal and methylglyoxal
• Chapter 10 DJ-1 as a biomarker of Parkinson's disease
• Chapter 11 Roles of DJ-1 in diabetes mellitus
• Chapter 12 Therapeutic activities of DJ-1 and its binding compounds against neurodegenerative diseases
• Chapter 13 DJ-1 as an oncogene and promising target for cancer chemotherapy. .