Protein-Protein and Domain-Domain Interactions

• Κύριοι συγγραφείς: Kangueane, Pandjassarame (Συγγραφέας, http://id.loc.gov/vocabulary/relators/aut), Nilofer, Christina (http://id.loc.gov/vocabulary/relators/aut)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2018.
• Έκδοση: 1st ed. 2018.
• Θέματα: Medical genetics.; Bioinformatics.; Proteins .; Vaccines.; Gene Function.; Computational Biology/Bioinformatics.; Protein Science.; Vaccine.

This book illustrates the importance and significance of the molecular (physical and chemical) and evolutionary (gene fusion) principles of protein-protein and domain-domain interactions towards the understanding of cell division, disease mechanism and target definition in drug discovery. It describ...

Πίνακας περιεχομένων:

• Module 1. Preface
• Module 2. Introduction to protein complexes
• Module 3. Historical advancement
• Module 4. Databases for protein complexes
• Module 5. Types of protein complexes
• Module 6. Hetero dimer protein complexes
• Module 7. Homo dimer protein complexes
• Module 8. Multimer protein complexes
• Module 9. Interfaces in protein complexes
• Module 10. Principles of protein-protein binding
• Module 11. Homodimer folding and binding
• Module 12. Gene fusion and protein complexes
• Module 13. Domain-domain interactions
• Module 14. Protein docking: Methods, software tools and servers
• Module 15. Protein complexes, pathways and networks
• Module 16. Protein complexes and biological functions
• Module 17. Protein complexes in diseases
• Module 18. Protein complexes in drug discovery & vaccine development
• Module 19. Protein complexes in genome and proteome analysis
• Module 20. Conclusions & challenges.