Mid-size Drugs Based on Peptides and Peptidomimetics A New Drug Category /

• Main Authors: Tamamura, Hirokazu (Author, http://id.loc.gov/vocabulary/relators/aut), Kobayakawa, Takuya (http://id.loc.gov/vocabulary/relators/aut), Ohashi, Nami (http://id.loc.gov/vocabulary/relators/aut)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Singapore : Springer Singapore : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Series: SpringerBriefs in Pharmaceutical Science & Drug Development,
• Subjects: Medicinal chemistry.; Pharmaceutical technology.; Organic chemistry.; Medicinal Chemistry.; Pharmaceutical Sciences/Technology.; Organic Chemistry.

This brief describes studies conducted by the authors on mid-size drugs utilizing peptides and peptidomimetics, and on the development of anti-HIV agents. Peptides are important biological molecules and have various physiological actions. Peptide-based drug discovery may help bring about the develop...

Table of Contents:

• 1. Introduction of Mid-Size Drugs and Peptidomimetics
• 2. Chloroalkene Dipeptide Isosteres as Peptidomimetics
• 3. Conformational-restricted Cyclic Peptides
• 4. Peptidomimetics that Mimic Secondary Structures of Peptides
• 5.Peptidomimetics that Mimic Tertiary Structures of Peptides
• 6. Conjugated Compounds Involving Peptides
• 7. Summary and Future Perspectives of Researches on Mid-Size Drugs.