HIV Vaccines and Cure The Path Towards Finding an Effective Cure and Vaccine /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Zhang, Linqi (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Lewin, Sharon R. (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2018.
• Έκδοση: 1st ed. 2018.
• Σειρά: Advances in Experimental Medicine and Biology, 1075
• Θέματα: Virology.; Vaccines.; Immunology.; Animal models in research.; Vaccine.; Animal Models.

This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate...

Πίνακας περιεχομένων:

• HIV Vaccine Efficacy Trials: RV144 and beyond
• HIV T-cell vaccines
• HIV broadly neutralizing antibodies: VRC01 and beyond
• Structural features of broadly neutralizing antibodies and rational design of vaccine
• Monkey models and HIV vaccine research
• Treatment of HIV for the Prevention of Transmission in Discordant Couples and at the Population Level
• HIV persistence on antiretroviral therapy and barriers to a cure
• The molecular biology of HIV latency
• Cellular determinants of HIV persistence on antiretroviral therapy
• In Vitro and In Vivo Models of HIV Latency
• Measuring HIV persistence on antiretroviral therapy
• Clinical interventions in HIV cure research.