Chromosome Translocation
This volume discusses various aspects of mechanisms and methodologies of chromosome translocations, ranging from a historical and clinical overview of chromosome translocations to the rapid development of the next-generation sequencing technologies, which has dramatically increased our understanding...
| Συγγραφή απο Οργανισμό/Αρχή: | |
|---|---|
| Άλλοι συγγραφείς: | |
| Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Singapore :
Springer Singapore : Imprint: Springer,
2018.
|
| Έκδοση: | 1st ed. 2018. |
| Σειρά: | Advances in Experimental Medicine and Biology,
1044 |
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Chapter 1: Historical and clinical overview of chromosome translocations
- Chapter 2: Next generation sequencing to identify chromosome translocation
- Chapter 3: The experimental models to study chromosome translocations
- Chapter 4: High throughput translocation sequencing to identify mechanistic factors shaping translocatome
- Chapter 5: Live cell imaging to study chromosome translocation
- Chapter 6: CRISPR/Cas9 to induce chromosome translocation in vivo
- Chapter 7: Generation of DNA double strand breaks (DSBs)
- Chapter 8: The role of DSB response pathway in regulating chromosome translocation
- Chapter 9: DSB repair and ligation of chromosome translocation
- Chapter 10: 3D genome organization defines the chromosome translocation pattern
- Chapter 11: Mechanisms of chromosome deletion
- Chapter 12: Chromothripsis: The role of DNA double strand break form on repair pathway selection.
