Neurotoxicity of Aluminum

• Corporate Author: SpringerLink (Online service)
• Other Authors: Niu, Qiao (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Singapore : Springer Singapore : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Series: Advances in Experimental Medicine and Biology, 1091
• Subjects: Neurosciences.; Pharmacology.; Neurobiology.; Pharmacology/Toxicology.

This book reviews the scientific literature and the authors' own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer's disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, and its relation to neurofibrillary tan...

Table of Contents:

• Overview of the relationship between aluminum exposure and health of human being
• The Chemistry of Human Exposure to Aluminum
• Entry and Deposit of Aluminum in Brain
• Aluminum as a CNS and immune system toxin across the life span
• Occupational exposure to aluminum and cognitive impairment
• Exposure to aluminum in daily life and Alzheimer's disease
• Animal model of aluminum-induced Alzheimer's Disease
• Aluminum induced neural cells death
• Aluminum-induced electrophysiological variation, synaptic plasticity impairment and related mechanism
• Cross talk between Aluminum and genetic susceptibility and epigenetic modification in Alzheimer's disease.