Engineering a Robust DNA Circuit for the Direct Detection of Biomolecular Interactions

• Main Author: Yan Shan, Ang (Author, http://id.loc.gov/vocabulary/relators/aut)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Singapore : Springer Singapore : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Biochemical engineering.; Bioinformatics.; Nanotechnology.; Systems biology.; Biological systems.; Biochemical Engineering.; Computational Biology/Bioinformatics.; Nanotechnology and Microengineering.; Systems Biology.

This book provides essential insights into designing a localized DNA circuit to promote the rate of desired hybridization reactions over undesired leak reactions in the bulk solution. The area of dynamic DNA nanotechnology, or DNA circuits, holds great promise as a highly programmable toolbox that c...