Implication of Quorum Sensing System in Biofilm Formation and Virulence

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Pallaval Veera Bramhachari (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2018.
• Έκδοση: 1st ed. 2018.
• Θέματα: Medical microbiology.; Microbiology.; Gene expression.; Parasitology.; Medical Microbiology.; Gene Expression.

 This book illustrates the importance and significance of Quorum sensing (QS), it's critical roles in regulating diverse cellular functions in microbes, including bioluminescence, virulence, pathogenesis, gene expression, biofilm formation and antibiotic resistance. Microbes can coordinate population behavior with small molecules called autoinducers (AHL) which serves as a signal of cellular population density, triggering new patterns of gene expression for mounting virulence and pathogenesis. Therefore, these microbes have the competence to coordinate and regulate explicit sets of genes by sensing and communicating amongst themselves utilizing variety of signals. This book descry emphasizes on how bacteria can coordinate an activity and synchronize their response to external signals and regulate gene expression. The chapters of the book provide the recent advancements on various functional aspects of QS systems in different gram positive and gram negative organisms. Finally, the book also elucidates a comprehensive yet a representative description of a large number of challenges associated with quorum sensing signal molecules viz. virulence, pathogenesis, antibiotic synthesis, biosurfactants production, persister cells, cell signaling and biofilms, intra and inter-species communications, host-pathogen interactions, social interactions & swarming migration in biofilms. 

 Module 1_Introduction to Microbial Quorum Sensing -- Module 2_Functional Aspects of Quorum Sensing in Microbes -- Module 3_Quorum Sensing regulated behaviors in Fungi -- Module 4_Quorum Sensing regulated behaviours in Gram- Negative bacteria -- Module 5_QS-regulated behaviours in Gram- Positive bacteria.