Diabetes Mellitus A risk factor for Alzheimer's Disease /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Nakabeppu, Yusaku (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Ninomiya, Toshiharu (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2019.
• Έκδοση: 1st ed. 2019.
• Σειρά: Advances in Experimental Medicine and Biology, 1128
• Θέματα: Neurosciences.; Diabetes.; Neurology .; Neurology.

This book describes the precise mechanisms by which insulin resistance and diabetes mellitus (DM) act as risk factors for Alzheimer's disease (AD). It opens by discussing the de novo synthesis of insulin in the brain and its functional significance with regard to glucose metabolism and maintena...

Πίνακας περιεχομένων:

• Chapter 1 Origins of brain insulin and its function
• Chapter 2 Epidemiological evidence of the relationship between diabetes and dementia
• Chapter 3 Molecular pathophysiology of insulin depletion, mitochondrial dysfunction, and oxidative stress in Alzheimer's Disease Brain
• Chapter 4 The Full Spectrum of Alzheimer's Disease is Rooted in Metabolic
• Derangements That Drive Type 3 Diabetes
• Chapter 5 The roles of apolipoprotein E, lipids and glucose in the pathogenesis of Alzheimer's disease
• Chapter 6 Molecular connection between diabetes and dementia
• Chapter 7 Type II Diabetes mellitus accelerates age-dependent A pathology in cynomolgus monkey brain
• Chapter 8 Diabetes-related dementia
• Chapter 9 Tortuous paths of insulin signaling and mitochondria in Alzheimer's disease
• Chapter 10 Mammalian target of rapamycin at the crossroad between Alzheimer's Disease and diabetes
• Chapter 11 Therapeutic strategies for Alzheimer's disease in the view of diabetes mellitus.