Antimicrobial Peptides Basics for Clinical Application /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Matsuzaki, Katsumi (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2019.
• Έκδοση: 1st ed. 2019.
• Σειρά: Advances in Experimental Medicine and Biology, 1117
• Θέματα: Pharmacology.; Biophysics.; Biological physics.; Biochemistry.; Cancer research.; Pharmacology/Toxicology.; Biological and Medical Physics, Biophysics.; Biochemistry, general.; Cancer Research.

This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I),...

Πίνακας περιεχομένων:

• Part 1. Introduction
• Chapter 1. Antimicrobial peptides of multicellular organisms: My perspective
• Part 2. Mechanisms of Antimicrobial Action
• Chapter 2. Membrane permeabilization mechanisms
• Chapter 3. Elementary processes and mechanisms of interactions of antimicrobial peptides with membranes
• - single GUV studies
• --
• Chapter 4. The mechanisms of action of cationic antimicrobial peptides refined by novel concepts from biophysical investigations
• Chapter 5. Anionic lipid clustering model
• Chapter 6. Intracellular antimicrobial peptides targeting the protein synthesis machinery
• Part 3. Other activities of AMPs
• Chapter 7. Antimicrobial and cell-penetrating peptides: How to understand two distinct functions despite similar physicochemical properties
• Chapter 8. Synthetic anti-lipopolysaccharide peptides (SALP) as effective inhibitors of pathogen-associated molecular patterns (PAMPs)
• Chapter 9. Anti-cancer activities of natural and synthetic peptides
• Chapter 10. Antimicrobial host defence peptides: Immunomodulatory functions and translational prospects
• Part 4. Towards Clinical Applications
• Chapter 11. Activity and selectivity of antimicrobial peptides: A complex interplay of multiple equilibria
• Chapter 12. Design of antimicrobial peptides: Progress made with human cathelicidin LL-37
• Chapter 13. Application of synthetic molecular evolution to the discovery of antimicrobial peptides
• Chapter 14. AMPs as anti-biofilm agents for human therapy and prophylaxis
• Chapter 15. Clinical application of AMPs. .