Progranulin and Central Nervous System Disorders

This book presents the latest knowledge on the roles of progranulin (PGRN) in normal physiology and pathology and explores the emerging significance of PGRN as a therapeutic target and biomarker in various CNS disorders, including frontotemporal lobe degeneration and other neurodegenerative diseases...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Hara, Hideaki (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Hosokawa, Masato (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Nakamura, Shinsuke (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Shimohata, Takayoshi (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Nishihara, Masugi (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2019.
Έκδοση:1st ed. 2019.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Chapter 1. Molecular and Functional Properties of Progranulin
  • Chapter 2. Progranulin as a biomarker for neurodegenerative diseases
  • Chapter 3. PGRN and FTLD
  • Chapter 4. PGRN and neurodegenerative diseases other than FTLD
  • Chapter 5. Progranulin Regulations of Lysosomal Homeostasis and its Involvement in Neurodegenerative Diseases
  • Chapter 6. Molecular and Functional Properties of Progranulin
  • Chapter 7. PGRN and neuroinflammation
  • Chapter 8. Neural Stem/Progenitor Cells and Progranulin
  • Chapter 9. Generation and phenotyping of progranulin-deficient mice
  • Chapter 10. Pleiotropic protective effects of progranulin in the treatment of ischemic stroke
  • Chapter 11. New therapeutic approaches against ocular diseases.