Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules The Shape of Organic Synthesis to Come /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Kobayashi, Yuichi (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2019.
• Έκδοση: 1st ed. 2019.
• Θέματα: Organic chemistry.; Medicinal chemistry.; Pharmacy.; Organic Chemistry.; Medicinal Chemistry.

This book describes cutting-edge organic syntheses of biologically active compounds, isolation of pharmaceutically promising compounds from microorganisms, drug design, and progress on chemical biology. Synthetic strategy and tactics are summarized for super-carbon chain compounds, antitumor polycyc...

Πίνακας περιεχομένων:

• 1. Microbial Fraction Library: A Screening Source for Drug Discovery
• 2. Efficient Total Synthesis of Ōmura Natural Products
• 3. Enantioselective Total Synthesis of the Antitumor Polycyclic Natural Products, FR182877 and Taxol
• 4. Synthetic Approaches on the Pluramycin-class Antibiotics
• 5. Recent Progress Toward the Total Synthesis of Duocarmaycins A and SA, Yatakemaycin, and PDE-I and -II
• 6. Structure-Activity Relationship Studies of Maitotoxin Based on Chemical Synthesis
• 7. Substitution of Allylic Picolinates with Various Copper Reagents and Synthetic Applications
• 8. Total Synthesis of Ingenol
• 9. Strategies for Synthesis of Anti-inflammatory Metabolites of Unsaturated Fatty Acids
• 10. Biosynthesis, biological functions, and receptors of leukotriene B4 and 12(S)-hydroxyheptadecatrienoic acid
• 11. Synthesis of classical/non-classical hybrid cannabinoids and related compounds
• 12. Exploring bioactive marine natural products and identification of their molecular targets
• 13. Target protein chemical modification
• 14. Target Identification of Bioactive Compounds by Photoaffinity Labeling Using Diazido Probes.