Drug Discovery in Japan Investigating the Sources of Innovation /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Nagaoka, Sadao (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Singapore : Springer Singapore : Imprint: Springer, 2019.
• Edition: 1st ed. 2019.
• Subjects: Economic policy.; Management.; Industrial management.; Japan-History.; R & D/Technology Policy.; Innovation/Technology Management.; History of Japan.

This book analyzes the drug-discovery process in Japan, based on detailed case studies of 12 groups of 15 innovative drugs. It covers the first statin in the world up to the recent major breakthrough in cancer therapy, the recent immune checkpoint inhibitor, the scientific discovery for which a 2018...

Table of Contents:

• Foreword
• Acknowledgement
• Chapter 1: Introduction
• Chapter 2: Compactin
• Chapter 3: Pravastatin (Pravachol, Mevalotin)
• Chapter 4: Rosuvastatin(Crestor)
• Chapter 5: Leuprorelin (Leuplin, Lupron, Viadur)
• Chapter 6: Oflaxacin and levofloxacin (Tarivid/Cravit)
• Chapter 7: Tamsulosin (Harnal, Flomax, OMNIC)
• Chapter 8: Pranlukast (Onon)
• Chapter 9: Tacrolimus (Prograf)
• Chapter 10: Pioglitazone (Actos, Glustin)
• Chapter 11: Donepezil (Aricept)
• Chapter 12: Candesartan (Blopress, Atacand)
• Chapter 13: Tocilizumab (Actemra,Ro-actemra)
• Chapter 14: Nivolumab (Opdivo)
• Chapter 15: Sources of innovation of drug discovery in Japan and its implications.