Antibacterial Drug Discovery to Combat MDR Natural Compounds, Nanotechnology and Novel Synthetic Sources /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Ahmad, Iqbal (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Ahmad, Shamim (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Rumbaugh, Kendra P. (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2019.
• Έκδοση: 1st ed. 2019.
• Θέματα: Medical microbiology.; Pharmacology.; Infectious diseases.; Bacteriology.; Nanotechnology.; Medical Microbiology.; Pharmacology/Toxicology.; Infectious Diseases.

This book compiles the latest information in the field of antibacterial discovery, especially with regard to the looming threat of multi-drug resistance. The respective chapters highlight the discovery of new antibacterial and anti-infective compounds derived from microbes, plants, and other natural...

Πίνακας περιεχομένων:

• Antibacterial drug discovery: perspective insights
• Section A: The Challenge of Antibiotic Resistance and Tolerance
• Problematic Groups of Multidrug Resistant Bacteria and their Resistance Mechanisms
• Emergence and spread of multi-drug resistance in ocular bacterial pathogens: A current update
• Antibiotic resistance in Campylobacter jejuni: mechanism, status and public health significance
• Mechanisms of biofilm development, antibiotic resistance & tolerance and their role in persistent infections
• Developing in vivo infection models with MDR pathogens for evaluating compound efficacy
• Section B. New antibiotic drug discovery approaches and progress
• Endophytes: a hidden treasure of novel antimicrobial metabolites
• Alternative therapies to antibiotics to combat drug-resistant bacterial pathogens
• In silico molecular modeling: key technologies in the drug discovery process to combat multidrug resistance
• Computational approaches for antibacterial drug discovery
• Efflux pump inhibitors and their role in the reversal of drug resistance
• Medicinal plants as a reservoir of new structures for anti-infective compounds
• Essential oils: Potential application in disease management
• Exploration of soil resistome through a metagenomic approach
• Actinomycetes as a continued source of new antibacterial leads
• Are Ancient Remedies the New Answer to Fighting Infections?
• Section C. Alternative antibiotic resistance treatment strategies
• Pre and probiotics: Using functional foods in the fight against microbial resistance to antibiotics
• Combination of drugs: an effective approach for enhancing the efficacy of antibiotics to combat drug resistance
• Targeted delivery of antibiotics using microparticles to combat multi-drug-resistant tuberculosis
• Practical applications of bacteriophage therapy: biofilms to bedside
• Inhibition of Quorum sensing; prospects in disease control
• Approaches for disrupting tissue-associated biofilms
• Nanomedicine and nanoemulsion in increasing the availability of antibiotics
• Nanoparticles as new emerging antibacterials: potential and limitation
• Nanomaterials as a novel class of anti-infective agents that attenuate bacterial quorum sensing
• Nanoparticle-based drug delivery systems: promising approaches against bacterial infections
• Green synthesis of metal nanoparticles: characterization and their antibacterial efficacy.