Neuroglia in Neurodegenerative Diseases

• Corporate Author: SpringerLink (Online service)
• Other Authors: Verkhratsky, Alexei (Editor, http://id.loc.gov/vocabulary/relators/edt), Ho, Margaret S. (Editor, http://id.loc.gov/vocabulary/relators/edt), Zorec, Robert (Editor, http://id.loc.gov/vocabulary/relators/edt), Parpura, Vladimir (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Singapore : Springer Singapore : Imprint: Springer, 2019.
• Edition: 1st ed. 2019.
• Series: Advances in Experimental Medicine and Biology, 1175
• Subjects: Neurosciences.; Neurology .; Molecular biology.; Neurology.; Molecular Medicine.

This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. Neuroglia are the most abundant cells in the nervous system and consist of several distinct cell types, such as astrocytes, oligodendrocytes,and microglia. Accumulating evidence suggests that neurogli...

Table of Contents:

• Introduction to neuroglia: history, definition, development and main functions
• Evolution of astroglia
• Physiology of astroglia
• Glicoryne system: glial cells as secretory cells of the CNS
• Physiology of oligodendroglia and NG-2 glia
• Physiology of microglia
• General pathophysiology of neuroglia
• Neuroglia in ageing
• In vivo imaging of neuroglia in neurodegenerative diseases
• Astroglia in leukodystrophies
• Astrocytes in ALS
• Astroglia in Alzheimer's disease
• Oligodendrogia in Alzheimer's disease
• Microglia in AD
• Neuroglia in Parkinson's disease
• Neuroglia in Huntington disease
• Neuroglia as a therapeutic target
• Stem cell derived neuroglia: new tool for research and treatment of neurodegenerative diseases.