Bioinformatics of Non Small Cell Lung Cancer and the Ras Proto-Oncogene

• Main Authors: Kashyap, Amita (Author), Bujamma, D. (Author), Babu M, Naresh (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Singapore : Springer Singapore : Imprint: Springer, 2015.
• Series: SpringerBriefs in Applied Sciences and Technology,
• Subjects: Engineering.; Cancer research.; Health informatics.; Bioinformatics.; Applied mathematics.; Engineering mathematics.; Computational intelligence.; Biomedical engineering.; Computational Intelligence.; Computational Biology/Bioinformatics.; Cancer Research.; Biomedical Engineering.; Health Informatics.; Appl.Mathematics/Computational Methods of Engineering.

Cancer is initiated by activation of oncogenes or inactivation of tumor suppressor genes. Mutations in the K-ras proto-oncogene are responsible for 10–30% of adenocarcinomas. Clinical Findings point to a wide variety of other cancers contributing to lung cancer incidence. Such a scenario makes ident...