Impact of hepatitis c virus core genetic variability on hcv-induced hepatocellular carcinoma development, via regulation of the wnt/ b-catenin cellular pathway

• Main Author: Άιχερ, Στεφανή
• Other Authors: Πουλάς, Κωνσταντίνος
• Format: Thesis
• Language: English
• Published: 2019
• Subjects: Hepatitis c virus; Hepatocellular carcinoma; Wnt/b-catenin; Ιός της ηπατίτιδας c; Ηπατοκυτταρικό καρκίνωμα; Wnt/β-κατενίνη; 616.362 3

Clinical studies have suggested that some hepatitis c virus (hcv) genotypes or isolates are associated with disease progression and hepatocellular carcinoma development (hcc). In addition to its known role in viral particle, hcv core protein may be directly involved in these pathogenic features a...