Current insight into kidney fibrosis and the role of EGFR as a potential therapeutic target

• Main Author: Κουκουτσίδη, Παναγιώτα
• Other Authors: Koukoutsidi, Panagiota
• Language: English
• Published: 2023
• Subjects: Epidermal growth factor receptor (EGFR); Chronic Kidney Disease (CKD); Renal fibrosis; TGF-β; Υποδοχέας του επιδερμικού αυξητικού παράγοντα (EGFR); Χρόνια νεφρική νόσος; Νεφρική ίνωση

The epidermal growth factor receptor (EGFR) is a member of the ErbB/HER family of receptors and its expression can be detected in almost every tissue of the human body. EGFR is a receptor tyrosine kinase with 11 known ligands. Over the years, researchers have conducted numerous experiments to determ...