Stereotactic body radiation therapy for prostate cancer

• Κύριος συγγραφέας: Ευστρατίου, Άγγελος
• Άλλοι συγγραφείς: Efstratiou, Angelos
• Γλώσσα: English
• Έκδοση: 2023
• Θέματα: Stereotactic body radiotherapy; Prostate advances in comparative evidence; Prostate cancer; PACE protocol; Στερεοτακτική ακτινοθεραπεία; Καρκίνος προστάτη

Stereotactic body radiation therapy (SBRT) is a method of radiation therapy with external radiation that its main differentiation from conventional radiation therapy is the sub fractionation of the total dose that will be received by the patient. Specifically, in terms of prostate stereotaxis, the total dose (36.25 Gy) is usually divided into 5 fractions of 7.25 Gy versus conventional radiation therapy in which up to 39 sessions take place with a total dose of up to 78 Gy (i.e. 2 Gy per session). As can be seen, in stereotactic radiation therapy a much greater degree of precision is necessary because of the highest doses per fraction received by the patient. The purpose of this thesis is the research and application of the Pace-B protocol in patients with prostate cancer, and the development of a template to streamline and automate the entire procedure, simplifying the workflow and increasing efficiency. Basic individual objectives are the study for the imaging of the patient, the necessary preparation before each radiation, immobilization during radiotherapy, the margins on the structures (CTV, PTV, bladder, rectum etc.) as well as the necessary dose limits to be applied.