Angiogenesis measurements in mammography using time-resolved dual energy analysis

• Κύριος συγγραφέας: Μπίλλας, Ηλίας
• Άλλοι συγγραφείς: Παναγιωτάκης, Γιώργος
• Μορφή: Thesis
• Γλώσσα: English
• Έκδοση: 2012
• Θέματα: Dual energy; Contrast enhanced digital mammography; Breast cancer; Simulation; CMOS APS; Διπλή ενέργεια; Ενίσχυση αντίθεσης στην ψηφιακή μαστογραφία; Καρκίνος μαστού; Προσομοίωση; 618.190 757 2

The aim of this project is the application of Dual Energy technique in breast phantoms using Complimentary-Metal-Oxide-Semiconductor (CMOS)Active-Pixel-Sensor (APS). This includes both, lab experimentation on developed breast phantoms, as well as simulations validating the results. Initially, phantoms were carefully prepared simulating the properties of real breast tissue and were imaged using X-ray unit. The next step in this project involved image processing and data representation. Using the dual energy technique, different concentrations of contrast agent (Iodine) were measured to relate clinical to medium kinetic measurements. With respect to this projects‟ clinical application, the implementation of this technique can be used to evaluate the iodine projected thickness (mg/cm2) using Contrast Enhanced Digital Mammography (CEDM) based on Dual Energy technique for the breast cancer detection.