Μελέτη απορροφούμενης δόσης και ποιότητα εικόνας σε δυναμικά νεφρογράμματα παιδιών με 99mTc-MAG3

• Κύριος συγγραφέας: Λέτσας, Βασίλειος
• Άλλοι συγγραφείς: Παναγιωτάκης, Γεώργιος
• Μορφή: Thesis
• Γλώσσα: English
• Έκδοση: 2013
• Θέματα: Nuclear medicine; Dynamic pediatric Renograms; Image-based; Person specific dosimetry; MAG3; Πυρηνική ιατρική; Δυναμικά παιδιατρικά νεφρογράμματα; 612.014 480 287

Renogram in Nuclear Medicine is the main examination for the diagnosis of several diseases in children such as kidney failure or obstructive uropathy. The dosimetry of this examination is based on the group-specific values presented by the ICRP publications. The need for person-specific dosimetry in the Nuclear Medicine urged in the creation of a new image-based dosimetric method, based on the outcome of the examination of the renogram of each patient. With the help of an experimental procedure, the percentage of self-absorption inside the “source” organs and the absorption from the surrounding tissues of the transmitted radiation of the radiopharmaceutical (99m-Tc-MAG3) is calculated, leading with the use of the MIRD method, to the measurement of the activity of Technetium inside the patient’s organs during the renogram’s duration. Afterwards with the help of theoretical models, conclusions and assumptions the total cumulated activity of the patient’s organs is calculated. The results show similar values with other projects published, which were more invasive and less cost-effective for the department.