An in vitro study, evaluating the effect of sunitinib and/or lapatinib on two glioma cell lines

• Main Authors: Giannopoulou, Efstathia, Dimitropoulos, Konstantinos, Argyriou, Andreas, Koutras, Angelos, Dimitrakopoulos, Fotinos, Kalofonos, Haralabos
• Other Authors: Γιαννοπούλου, Ευσταθία
• Format: Journal (paper)
• Language: English
• Published: 2013
• Subjects: Lapatinib; Sunitinib; Malignant glioma; Proliferation; Apoptosis; Migration; MMPs; Κακοήθες γλοίωμα; Πολλαπλασιασμός; Απόπτωση; Μετανάστευση

Aim: We sought to assess the effect of sunitinib and lapatinib applied either alone or in combination, on U87 and M059K glioma cells. Methods: Both cell lines were cultured as recommended by the manufacturer. Sunitinib and lapatinib were applied, either separately or in combination, in the culture...