Βελτιστοποίηση μιας καινοτόμου ιατρικής συσκευής θεραπείας του γλαυκώματος

• Κύριος συγγραφέας: Παπαστάθης, Ευστάθιος
• Άλλοι συγγραφείς: Ματσόπουλος, Γεώργιος
• Μορφή: Thesis
• Γλώσσα: English
• Έκδοση: 2015
• Θέματα: Glaucoma; Implant; Modelling; Simulation; Optimization; Γλαύκωμα; Εμφύτευμα; Μοντελοποίηση; Προσομοίωση; Βελτιστοποίηση; 617.741 059

The present work deals with the fluidic analysis of a glaucoma drainage device, which involves modelling, three-dimensional computational fluid dynamic work of a rather difficult optimization problem involving strong nonlinearities. The results have been accompanied by in-vitro experiments in order to evaluate and finally demonstrate the power of computational analysis. The results of this work have been transferred and are applicable right away to the development of a commercial novel medical device. This study can be considered as applied and technological research. The deliverables include a user-friendly graphical interface designed in MATLAB and also drawings of the proposed optimized geometry. In the following chapters are presented the literature review about the disease, the mathematical background and the available materials and methods that are used as well. The main idea behind this report was that the study should be reproducible at any time. Therefore, special attention was paid to the way of presenting the settings of all the software that was used. The last two chapters present the results and the discussion respectively.