Molecular and biochemical mechanisms in streptozotocin-induced diabetes and associated behavioral indices

• Main Author: Κοκκόσης, Αλέξανδρος
• Other Authors: Μαργαρίτη, Μαριγούλα
• Format: Thesis
• Language: English
• Published: 2015
• Subjects: Type I diabetes; Cognitive dysfunction; Cholinergic system; Oxidative stress; Neuronal apoptosis; Brain regions; Διαβήτης τύπου Ι; Γνωστικές δυσλειτουργίες; Χολινεργικό σύστημα; Οξειδωτικό στρές; Νευρωνική απόπτωση; Εγκεφαλικές περιοχές; 616.462 206 107 24

Diabetic encephalopathy, characterized by impaired cognitive function may involve neuronal dysfunction and neurochemical abnormalities. Here we investigated the effects of streptozotocin-induced type I diabetes (T1D) and its treatment by insulin on behavioral indices and the neurochemical profile in...