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oapen-20.500.12657-315442021-11-12T16:22:05Z Next Generation Sequencing - Advances, Applications and Challenges Kulski, Jerzy K molecular biology biochemistry genetics bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences. 2017-04-12 23:55 2019-10-04 14:42:00 2020-04-01T13:39:02Z 2020-04-01T13:39:02Z 2016 book 627315 OCN: 1030819120 9789535122401 http://library.oapen.org/handle/20.500.12657/31544 eng InTechOpen 10.5772/60489 10.5772/60489 09f6769d-48ed-467d-b150-4cf2680656a1 03044c74-f902-48c3-800a-209b3ec88c71 9789535122401 open access
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Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.
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