612584.pdf
Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and...
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InTechOpen
2019
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oapen-20.500.12657-323482021-11-12T16:24:46Z Chapter 15 Brain Tumors and the Lynch Syndrome Peltomäki, Päivi Gylling, Annette brain tumors lynch syndrome brain tumors lynch syndrome Colorectal cancer DNA methylation DNA mismatch repair Gene Glioblastoma Glioma Hereditary nonpolyposis colorectal cancer Mutation Neoplasm bic Book Industry Communication::P Mathematics & science::PD Science: general issues Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and is estimated to account for 1-6% of all colorectal cancers (Lynch & de la Chapelle, 2003). 2019-10-04 14:27:25 2020-04-01T14:07:02Z 2016-08-01 23:55 2019-10-04 14:27:25 2020-04-01T14:07:02Z 2016-12-31 23:55:55 2019-10-04 14:27:25 2020-04-01T14:07:02Z 2020-04-01T14:07:02Z 2011 chapter 612584 OCN: 1030821093 http://library.oapen.org/handle/20.500.12657/32348 eng application/pdf n/a 612584.pdf InTechOpen Management of CNS Tumors 10.5772/21293 10.5772/21293 09f6769d-48ed-467d-b150-4cf2680656a1 e4114cfa-bb48-49d8-9a08-d0338a9a7b48 7292b17b-f01a-4016-94d3-d7fb5ef9fb79 European Research Council (ERC) 1 232635 FP7 FP7 Ideas: European Research Council FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Framework Programme of the European Community for Research, Technological Development and Demonstration Activities (2007 to 2013) open access |
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English |
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Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by
germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most
prevalent cancer syndromes in man and is estimated to account for 1-6% of all colorectal
cancers (Lynch & de la Chapelle, 2003). |
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2019 |
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