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oapen-20.500.12657-493672021-11-23T14:02:20Z Chapter Computer Assistance in the Minimally Invasive Ablation Treatment of Pancreatic Cancer Eigl, Benjamin Andreou, Andreas Peterhans, Matthias Weber, Stefan Gloor, Beat pancreatic cancer, needle guidance, irreversible electroporation, Computer-assisted surgery bic Book Industry Communication::M Medicine::MB Medicine: general issues The insertion of ablation needles towards pancreatic tumors demands excellent anatomical knowledge and interdisciplinary skills from the medical professional. While the placement of a single needle next to the structures at risk surrounding the pancreas is considered a challenging task, irreversible electroporation requires multiple needles to be placed in parallel at a specific location. Minimally invasive procedures complicate the already ambitious procedure, yet the ablation method bears potential to increase the overall survival for patients with locally advanced pancreatic cancer. Current studies require more clinical evidence regarding the efficacy of irreversible electroporation in pancreatic cancer by means of randomized controlled, multicenter trials. However, the ablation treatment is currently applied in expert centers only, which is due to the complex task of the needle placement. Computer-assisted surgery has shown its potential in different fields of applications to improve the targeting of diseased tissue and the confidence of the medical professional. The application of computer-assisted needle navigation for pancreatic cancer ablation holds the prospect to make the procedure more reproducible and safer. 2021-06-02T10:13:22Z 2021-06-02T10:13:22Z 2020 chapter ONIX_20210602_10.5772/intechopen.93226_481 https://library.oapen.org/handle/20.500.12657/49367 eng application/pdf n/a 72812.pdf InTechOpen 10.5772/intechopen.93226 10.5772/intechopen.93226 09f6769d-48ed-467d-b150-4cf2680656a1 H2020-MSCA-ITN-2016 722068 open access
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The insertion of ablation needles towards pancreatic tumors demands excellent anatomical knowledge and interdisciplinary skills from the medical professional. While the placement of a single needle next to the structures at risk surrounding the pancreas is considered a challenging task, irreversible electroporation requires multiple needles to be placed in parallel at a specific location. Minimally invasive procedures complicate the already ambitious procedure, yet the ablation method bears potential to increase the overall survival for patients with locally advanced pancreatic cancer. Current studies require more clinical evidence regarding the efficacy of irreversible electroporation in pancreatic cancer by means of randomized controlled, multicenter trials. However, the ablation treatment is currently applied in expert centers only, which is due to the complex task of the needle placement. Computer-assisted surgery has shown its potential in different fields of applications to improve the targeting of diseased tissue and the confidence of the medical professional. The application of computer-assisted needle navigation for pancreatic cancer ablation holds the prospect to make the procedure more reproducible and safer.
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