9783030657680.pdf

This open access volume will introduce recent discoveries in cancer metabolism since the publication of the first edition in 2018, providing readers with an up-to-date understanding of developments in the field. Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigen...

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Γλώσσα:English
Έκδοση: Springer Nature 2021
Διαθέσιμο Online:https://www.springer.com/9783030780982
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spelling oapen-20.500.12657-495222021-06-15T07:20:45Z The Heterogeneity of Cancer Metabolism Le, Anne Cancer Research Cancer Metabolism Cancer Therapy Cancer Biology open access personalized cancer treatment glucose metabolism glutamine metabolism metabolism biomarkers metabolic pathways drug treatments glioblastoma pancreatic cancer breast cancer renal cell carcinoma non-hodgkin's lymphoma cancer-associated fibroblasts tumor microenvironment covid-19 diabetes cardiovascular diseases gene profiles chemotherapeutic agenet clinical trials Oncology bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology This open access volume will introduce recent discoveries in cancer metabolism since the publication of the first edition in 2018, providing readers with an up-to-date understanding of developments in the field. Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, the authors delve into the complexity and diversity of cancer metabolism and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies for cancer treatment. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer treatment. This book has four major parts. Part one will cover the basic metabolism of cancer cells, followed by a discussion of the heterogeneity of cancer metabolism in part two. Part three addresses the relationship between cancer cells and cancer-associated fibroblasts, and the new part four will explore the metabolic interplay between cancer and other diseases. This new section makes the book unique from other texts currently available on the market. The second edition will be useful for cancer metabolism researchers, cancer biologists, epidemiologists, physicians, health care professionals in related disciplines, policymakers, marketing and economic strategists, among others. It may also be used in courses such as intro to cancer metabolism, cancer biology, and related biochemistry courses for undergraduate and graduate students. 2021-06-14T09:30:08Z 2021-06-14T09:30:08Z 2021 book ONIX_20210614_9783030657680_24 9783030657680 https://library.oapen.org/handle/20.500.12657/49522 eng Advances in Experimental Medicine and Biology application/pdf Attribution 4.0 International 9783030657680.pdf https://www.springer.com/9783030780982 Springer Nature Springer 10.1007/978-3-030-65768-0 10.1007/978-3-030-65768-0 6c6992af-b843-4f46-859c-f6e9998e40d5 a1893bf7-888c-4536-93b5-0af1a8895561 9783030657680 Springer 1311 271 [grantnumber unknown] open access
institution OAPEN
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language English
description This open access volume will introduce recent discoveries in cancer metabolism since the publication of the first edition in 2018, providing readers with an up-to-date understanding of developments in the field. Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, the authors delve into the complexity and diversity of cancer metabolism and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies for cancer treatment. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer treatment. This book has four major parts. Part one will cover the basic metabolism of cancer cells, followed by a discussion of the heterogeneity of cancer metabolism in part two. Part three addresses the relationship between cancer cells and cancer-associated fibroblasts, and the new part four will explore the metabolic interplay between cancer and other diseases. This new section makes the book unique from other texts currently available on the market. The second edition will be useful for cancer metabolism researchers, cancer biologists, epidemiologists, physicians, health care professionals in related disciplines, policymakers, marketing and economic strategists, among others. It may also be used in courses such as intro to cancer metabolism, cancer biology, and related biochemistry courses for undergraduate and graduate students.
title 9783030657680.pdf
spellingShingle 9783030657680.pdf
title_short 9783030657680.pdf
title_full 9783030657680.pdf
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title_full_unstemmed 9783030657680.pdf
title_sort 9783030657680.pdf
publisher Springer Nature
publishDate 2021
url https://www.springer.com/9783030780982
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