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oapen-20.500.12657-496112021-06-19T00:56:42Z Chapter Genomes Harb, Omar Boehme, Ulrike Crouch, Kathryn Ifeonu, Olukemi Roos, David Silva, Joana Silva-Franco, Fatima Svärd, Staffan Tretina, Kyle Weedall, Gareth biological sciences; genomes; parasitology; genomics research; eukaryotic parasites bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMF Pathology::MMFP Medical parasitology In the last decade, the rise of affordable affordable high-throughput sequencing technologies has led to rapid advances across the biological sciences. At the time of writing, annotated reference genomes are available within most clades of eukaryotic pathogens, and including un-annotated sequences over 550 genomes are available in total. This This has greatly facilitated studies in many areas of parasitology. In addition, the volume of functional genomics data, including analysis of differential differential transcription and DNA-protein interactions, has increased exponentially. With this unprecedented increase in publicly available data, tools to search and compare datasets are also becoming ever more important. A number of database resources are available, and access to these has become fundamental for a majority of research groups. This This chapter discusses the current state of genomics research for a number of eukaryotic parasites, discussing the genome and functional genomics resources available at the time of writing and highlighting functionally important or unique aspects of the genome for each group. In addition publicly accessible database resources pertaining to eukaryotic parasites are also discussed. 2021-06-17T11:31:08Z 2021-06-17T11:31:08Z 2016 chapter 9783709114155 9783709148792 https://library.oapen.org/handle/20.500.12657/49611 eng application/pdf Attribution 4.0 International Bookshelf_NBK556349.pdf Springer Nature Molecular Parasitology 6c6992af-b843-4f46-859c-f6e9998e40d5 bbcdfb0d-7955-484a-ba58-c13d3188c839 d859fbd3-d884-4090-a0ec-baf821c9abfd 9783709114155 9783709148792 Wellcome 37 Wellcome Trust Wellcome open access
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In the last decade, the rise of affordable affordable high-throughput sequencing technologies has led to rapid advances across the biological sciences. At the time of writing, annotated reference genomes are available within most clades of eukaryotic pathogens, and including un-annotated sequences over 550 genomes are available in total. This This has greatly facilitated studies in many areas of parasitology. In addition, the volume of functional genomics data, including analysis of differential differential transcription and DNA-protein interactions, has increased exponentially. With this unprecedented increase in publicly available data, tools to search and compare datasets are also becoming ever more important. A number of database resources are available, and access to these has become fundamental for a majority of research groups. This This chapter discusses the current state of genomics research for a number of eukaryotic parasites, discussing the genome and functional genomics resources available at the time of writing and highlighting functionally important or unique aspects of the genome for each group. In addition publicly accessible database resources pertaining to eukaryotic parasites are also discussed.
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