9788884539403.pdf
There is considerable interest today for the reactions of anticancer metallodrugs with proteins as these interactions might feature processes that are crucial for the biodistribution, the toxicity and even the mechanism of action of this important group of anticancer agents. Valuable structural and...
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Firenze University Press
2022
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| Διαθέσιμο Online: | https://books.fupress.com/isbn/9788884539403 |
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oapen-20.500.12657-54868 |
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oapen-20.500.12657-548682022-06-01T03:00:02Z Proteins as possible targets for antitumor metal complexes: biophysical studies of their interactions Gabbiani, Chiara Biologia Chimica bic Book Industry Communication::P Mathematics & science::PH Physics bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences There is considerable interest today for the reactions of anticancer metallodrugs with proteins as these interactions might feature processes that are crucial for the biodistribution, the toxicity and even the mechanism of action of this important group of anticancer agents. Valuable structural and functional information on these adducts could be derived from several biophysical studies mainly relying on the application of X-ray diffraction and ESI MS techniques. The structural and functional information achieved on the respective metallodrug–protein adducts allowed us to identify some general trends in the reactivity of anticancer metallodrugs with protein targets. 2022-05-31T10:15:26Z 2022-05-31T10:15:26Z 2009 book ONIX_20220531_9788884539403_152 2612-8020 9788884539403 9788884539397 9788892737679 https://library.oapen.org/handle/20.500.12657/54868 eng Premio Tesi di Dottorato application/pdf n/a 9788884539403.pdf https://books.fupress.com/isbn/9788884539403 Firenze University Press 10.36253/978-88-8453-940-3 10.36253/978-88-8453-940-3 bf65d21a-78e5-4ba2-983a-dbfa90962870 9788884539403 9788884539397 9788892737679 9 74 Firenze open access |
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OAPEN |
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English |
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There is considerable interest today for the reactions of anticancer metallodrugs with proteins as these interactions might feature processes that are crucial for the biodistribution, the toxicity and even the mechanism of action of this important group of anticancer agents. Valuable structural and functional information on these adducts could be derived from several biophysical studies mainly relying on the application of X-ray diffraction and ESI MS techniques. The structural and functional information achieved on the respective metallodrug–protein adducts allowed us to identify some general trends in the reactivity of anticancer metallodrugs with protein targets. |
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Firenze University Press |
| publishDate |
2022 |
| url |
https://books.fupress.com/isbn/9788884539403 |
| _version_ |
1771297399036182528 |
