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oapen-20.500.12657-554602022-06-01T03:35:22Z Cerebral Small Vessel Disease and Cerebral Amyloid Angiopathy Valenti, Raffaella bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine Sporadic cerebral small vessel disease (SVD) is considered to be among the most commonly known neuropathological processes in the brain, hosting a crucial role in stroke, cognitive impairment, and functional loss in elderly subjects. We investigated clinical (neuroimaging and cognitive) biomarkers in the SVD, through a series of analyses from our five studies. Sporadic cerebral SVD is a complex ‘micro-world’ to be globally considered. All the relevant lesion types and SVD neuroimaging burden should be taken into account. The cumulative effects of microangiopathy burden in the brain of patients affected by SVD are crucial. Cognitive rehabilitation could represent a promising approach to prevent vascular dementia or to improve cognitive performances in patients with cerebral SVD. Longitudinal studies may provide more robust information about the progression and prognostic significance of our findings. 2022-05-31T10:30:37Z 2022-05-31T10:30:37Z 2018 book ONIX_20220531_9788864537795_744 2612-8020 9788864537795 9788864537788 9788892730861 https://library.oapen.org/handle/20.500.12657/55460 eng Premio Tesi di Dottorato application/pdf Attribution 4.0 International 9788864537795.pdf https://books.fupress.com/isbn/9788864537795 Firenze University Press 10.36253/978-88-6453-779-5 10.36253/978-88-6453-779-5 bf65d21a-78e5-4ba2-983a-dbfa90962870 9788864537795 9788864537788 9788892730861 67 182 Florence open access
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OAPEN
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English
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| description |
Sporadic cerebral small vessel disease (SVD) is considered to be among the most commonly known neuropathological processes in the brain, hosting a crucial role in stroke, cognitive impairment, and functional loss in elderly subjects. We investigated clinical (neuroimaging and cognitive) biomarkers in the SVD, through a series of analyses from our five studies. Sporadic cerebral SVD is a complex ‘micro-world’ to be globally considered. All the relevant lesion types and SVD neuroimaging burden should be taken into account. The cumulative effects of microangiopathy burden in the brain of patients affected by SVD are crucial. Cognitive rehabilitation could represent a promising approach to prevent vascular dementia or to improve cognitive performances in patients with cerebral SVD. Longitudinal studies may provide more robust information about the progression and prognostic significance of our findings.
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9788864537795.pdf
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9788864537795.pdf
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9788864537795.pdf
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9788864537795.pdf
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9788864537795.pdf
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9788864537795.pdf
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9788864537795.pdf
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Firenze University Press
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2022
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https://books.fupress.com/isbn/9788864537795
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1771297482057187328
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