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oapen-20.500.12657-55512
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oapen-20.500.12657-555122022-06-01T03:37:57Z Histaminergic neurotransmission as a gateway for the effects of the fat sensing molecule Oleoylethanolamide Costa, Alessia bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology The histaminergic system is a pleiotropic system that commands general states of metabolism and consciousness, including learning and memorizing both pleasurable and aversive events. Brain histamine mediates the central effects of a signal molecule produced in the intestine, namely oleoylethanolamide (OEA). OEA is released by the enterocytes in response to high fat intake and reduces eating, by indirectly activating a subpopulation of histaminergic neurons. In her thesis, she explored other potential interactions between these two systems in the pursuit of unexplored neuronal mechanisms that may shed light on the mode of action of psychoactive agents and possibly lead to the development of new drugs. 2022-05-31T10:31:50Z 2022-05-31T10:31:50Z 2019 book ONIX_20220531_9788864539959_796 2612-8020 9788864539959 9788864539942 9788892730182 https://library.oapen.org/handle/20.500.12657/55512 eng Premio Tesi di Dottorato application/pdf Attribution 4.0 International 9788864539959.pdf https://books.fupress.com/isbn/9788864539959 Firenze University Press 10.36253/978-88-6453-995-9 10.36253/978-88-6453-995-9 bf65d21a-78e5-4ba2-983a-dbfa90962870 9788864539959 9788864539942 9788892730182 74 124 Florence open access
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OAPEN
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DSpace
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| language |
English
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| description |
The histaminergic system is a pleiotropic system that commands general states of metabolism and consciousness, including learning and memorizing both pleasurable and aversive events. Brain histamine mediates the central effects of a signal molecule produced in the intestine, namely oleoylethanolamide (OEA). OEA is released by the enterocytes in response to high fat intake and reduces eating, by indirectly activating a subpopulation of histaminergic neurons. In her thesis, she explored other potential interactions between these two systems in the pursuit of unexplored neuronal mechanisms that may shed light on the mode of action of psychoactive agents and possibly lead to the development of new drugs.
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| title |
9788864539959.pdf
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| spellingShingle |
9788864539959.pdf
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| title_short |
9788864539959.pdf
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| title_full |
9788864539959.pdf
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| title_fullStr |
9788864539959.pdf
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| title_full_unstemmed |
9788864539959.pdf
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| title_sort |
9788864539959.pdf
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| publisher |
Firenze University Press
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| publishDate |
2022
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| url |
https://books.fupress.com/isbn/9788864539959
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| _version_ |
1771297611099144192
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