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oapen-20.500.12657-55633
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oapen-20.500.12657-556332022-06-01T03:45:43Z Development of optical methods for real-time whole-brain functional imaging of zebrafish neuronal activity Turrini, Lapo zebrafish calcium imaging light-sheet microscopy epilepsy behaviour bic Book Industry Communication::M Medicine::MF Pre-clinical medicine: basic sciences::MFC Anatomy Each one of us in his life has, at least once, smelled the scent of roses, read one canto of Dante’s Commedia or listened to the sound of the sea from a shell. All of this is possible thanks to the astonishing capabilities of an organ, such as the brain, that allows us to collect and organize perceptions coming from sensory organs and to produce behavioural responses accordingly. Studying an operating brain in a non-invasive way is extremely difficult in mammals, and particularly in humans. In the last decade, a small teleost fish, zebrafish (Danio rerio), has been making its way into the field of neurosciences. The brain of a larval zebrafish is made up of 'only' 100000 neurons and it’s completely transparent, making it possible to optically access it. Here, taking advantage of the best of currently available technology, we devised optical solutions to investigate the dynamics of neuronal activity throughout the entire brain of zebrafish larvae. 2022-05-31T10:35:55Z 2022-05-31T10:35:55Z 2020 book ONIX_20220531_9788855180702_917 2612-8020 9788855180702 9788855180696 9788855180719 https://library.oapen.org/handle/20.500.12657/55633 eng Premio Tesi di Dottorato application/pdf Attribution 4.0 International 9788855180702.pdf https://books.fupress.com/isbn/9788855180702 Firenze University Press 10.36253/978-88-5518-070-2 10.36253/978-88-5518-070-2 bf65d21a-78e5-4ba2-983a-dbfa90962870 9788855180702 9788855180696 9788855180719 85 200 Florence open access
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OAPEN
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DSpace
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English
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| description |
Each one of us in his life has, at least once, smelled the scent of roses, read one canto of Dante’s Commedia or listened to the sound of the sea from a shell. All of this is possible thanks to the astonishing capabilities of an organ, such as the brain, that allows us to collect and organize perceptions coming from sensory organs and to produce behavioural responses accordingly. Studying an operating brain in a non-invasive way is extremely difficult in mammals, and particularly in humans. In the last decade, a small teleost fish, zebrafish (Danio rerio), has been making its way into the field of neurosciences. The brain of a larval zebrafish is made up of 'only' 100000 neurons and it’s completely transparent, making it possible to optically access it. Here, taking advantage of the best of currently available technology, we devised optical solutions to investigate the dynamics of neuronal activity throughout the entire brain of zebrafish larvae.
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| title |
9788855180702.pdf
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9788855180702.pdf
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| title_short |
9788855180702.pdf
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| title_full |
9788855180702.pdf
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| title_fullStr |
9788855180702.pdf
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9788855180702.pdf
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| title_sort |
9788855180702.pdf
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| publisher |
Firenze University Press
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| publishDate |
2022
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| url |
https://books.fupress.com/isbn/9788855180702
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1771297432676597760
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