Guide to techniques in mouse development /

• Άλλοι συγγραφείς: Wassarman, Paul M., DePamphilis, Melvin L.
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: San Diego : Academic Press, ©1993.
• Σειρά: Methods in enzymology ; v. 225.
• Θέματα: Molecular biology > Technique.; Mice as laboratory animals.; Developmental biology.; Souris > Développement.; Molecular Biology [MESH]; Mice [MESH]; Animals, Laboratory [MESH]; Laboratory animals; Electronic books.
• Φυσική περιγραφή: 1 online resource (xxxviii, 1021 pages) : illustrations.
• Βιβλιογραφία: Includes bibliographical references and indexes.
• ISBN: 0121821269; 9780121821265
• ISSN: 0076-6879 ;

This volume provides, for the first time, an extensive compilation of those state-of-the-art methods that have revolutionized the use of mice as an experimental system. This volume is a unique source for detailed descriptions to be used in research by both experienced and novice researchers - Germ cells and embryos; Fertilization; Gene expression: messenger RNA, reporter genes, proteins, methylation; Gene identification; Nuclear transplantation; Transgenic animals: pronuclear injection, embryonic stem cells, and gene targeting; Lineage analysis. Key Features * Contains the most up-to-date methodology as applied to mouse development * Focuses on molecular approaches to experimental mouse development * The first comprehensive source for molecular biological methods in mouse development * Many of the methods have never appeared before.