Biological mass spectrometry /

This volume describes and integrates the techniques and fundamentals of more than a decade of revolutionary advances in both chromatographic and mass spectrometric technologies that have enabled the direct investigation of biomacromolecules per se and have provided the analytical power base to usher...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Burlingame, A. L.
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Amsterdam ; Boston : Elsevier Academic Press, ©2005.
Σειρά:Methods in enzymology ; v. 402.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Περιγραφή
Περίληψη:This volume describes and integrates the techniques and fundamentals of more than a decade of revolutionary advances in both chromatographic and mass spectrometric technologies that have enabled the direct investigation of biomacromolecules per se and have provided the analytical power base to usher in the new fields of proteomics and systems biology. It also covers new biophysical applications such as H/D exchange for study of conformations, protein-protein and protein-metal and ligand interactions. Finally it describes atto-to-zepto-mole quantitation of 14C and 3H by accelerator mass spectrometry. *Part 1 of 2 volumes about Mass Spectrometry *Authoritative and comprehensive treatment of protein mass spectrometry in human cell biology *Presents fundamentals, techniques, instrumentation and bioinformatics *Provides an overview of proteomics, protein-protein and protein-ligand binding, and biophysical studies.
Φυσική περιγραφή:1 online resource (xxxiii, 478 pages, [4] pages of plates) : illustrations (some color).
Βιβλιογραφία:Includes bibliographical references and index.
ISBN:0121828077
9780121828073
ISSN:0076-6879 ;