Human herpesvirus-6 : general virology, epidemiology and clinical pathology /
The most comprehensive review available of all aspects of HHV-6 combining basic and clinical science.
| Άλλοι συγγραφείς: | , |
|---|---|
| Μορφή: | Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Amsterdam ; Boston :
Elsevier,
©2006.
|
| Έκδοση: | 2nd ed. |
| Σειρά: | Perspectives in medical virology ;
v. 12. |
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Foreword / Robert C. Gallo
- Foreword / Ronald Glaser, Marshall V. Williams
- Preface / Gerhard R.F. Krueger, Dharam V. Ablashi
- Discovery and Classification of Human Herpesvirus-6 (HHV-6) / Dharam V. Ablashi
- Ultrastructure and Assembly of Human Herpesvirus-6 (HHV-6) / Z. Hong Zhou, James K. Stoops, Gerhard R.F. Krueger
- HHV-6 Genome: Similar and Different / U.A. Gompels, F.C. Kasolo
- Proteins of HHV-6 / Yasuko Mori
- Biological Features of HHV-6 / Lorenzo Dagna, Fabio Santoro, Paolo Lusso
- Strain Variants of HHV-6 / Dharam V. Ablashi
- Serologic Testing for Acute and Chronic Infection / Henri Agut, Agnes Gautheret-Dejean
- Molecular Testing for HHV-6 Infection / Stephen Dewhurst, Birgit Bradel-Tretheway
- Epidemiology of HHV6 / Caroline Breese Hall
- Pathologic Features of HHV-6 Disease / Gerhard R.F. Krueger, Brigitte Schneider
- Systemic Reactions to HHV-6 Infection / Vincent Descamps, Emmanuel Mahe, Sylvie Ranger-Rogez
- HHV-6 and the Integument / Tetsushi Yoshikawa
- HHV-6 and the Respiratory System / Sebastian M. Schmidt, Helga Wiersbitzky, Siegfried K.W. Wiersbitzky
- HHV-6 and the Lympho-Hematopoietic System / Sylvie Ranger-Rogez, Aurelie Lacroix, François Denis, Dominique Bordessoule
- Human Herpesvirus-6 and the Cellular Immune System / Judith A. Britz
- HHV-6 and the Central Nervous System / Samantha S. Soldan, Andrew D. Goodman, Steven Jacobson
- HHV-6 and the Cardiovascular System / Satoki Fukae, Naoto Ashizawa
- HHV-6 in Cardiovascular Pathology / L. Maximilian Buja
- HHV-6, the Liver and the Gastrointestinal Tract / Tetsushi Yoshikawa
- HHV-6 in Chronic Fatigue Syndrome / Daniel Peterson, Lisa Atwell
- HHV-6 and HIV-1 Infection / Paolo Lusso
- Human Herpesvirus-6 Infection in Solid Organ and Stem Cell Transplant Recipients / P. Ljungman, N. Singh
- Therapeutic Approaches to HHV-6 Infection / Lieve Naesens, Leen De Bolle, Erik De Clercq
- Animal Models / Claude P. Genain
- Computational Simulation of HHV-6 Infection / Guanyu Wang, Gerhard R.F. Krueger
- Experimental Therapeutic Approaches.
- Cover
- Contents
- Foreword by Robert Gallo
- Foreword by Ronald Glaser and Marshall Williams
- Preface
- Part I: General Virology
- Discovery and Classification of Human Herpesvirus-6 (HHV-6)
- Discovery
- Nomenclature and classification
- References
- Ultrastructure and Assembly of Human Herpesvirus-6 (HHV-6)
- Introduction
- Herpesvirus-6 assembly and maturation
- Three-dimensional structure of HHV-6 capsid
- Comparision of the HHV-6 cappsid structure with those of other human herpesviruses
- Conclusion
- References
- HHV-6 Genome: Similar and Different
- Genome classification and biology
- Genomes, cellular tropism and laboratory culture
- Genome structure and repetitive sequence
- Genome rearrangements and relationship to other herpesviruses
- Genome composition and general molecular biology
- Herpesvirus conserved and HHV-6-specific genes
- Genomes and HHV-6 strains
- Acknowledgements
- References
- Proteins of HHV-6
- Introduction
- IE proteins
- U16/U17
- U53, proteinase
- U69, kinase
- Cellular homologues
- U94, AAV-2 rep homologue
- Envelope glycoproteins
- U39, gB
- U48 and U82, gH and gL
- U100, gQ
- U47, gO
- U11
- U14
- U27
- Perspective
- References
- Biological Features of HHV-6
- Introduction
- HHV-6 cellular receptor
- Species specificity
- Cellular tropism of HHV-6
- Biological effects of HHV-6 on the host cell
- References
- Part II: Diagnosis and Epidemiology
- Strain Variants of HHV-6
- Introduction
- Epidemiology
- Molecular biology
- Biological aspects of variants A and B
- Reactivity of monoclonal antibodies to HHV-6 variants A and B
- Disease associations of HHV-6A and -6B variants
- Concluding remarks
- References
- Serologic Testing for Acute and Chronic Infection
- Introduction
- Serologic assays
- Serologic findings
- Pending questions and perspectives
- Acknowledgments
- References
- Molecular Testing for HHV-6 Infection
- Introduction
- Primary infection: characteristics and diagnostic considerations
- PCR analysis of cell-free body fluids
- Reverse transcription PCR analysis
- Quantitative PCR analysis of HHV-6 DNA in PBMC or blood
- Detection of virus variants
- Other assay approaches
- Future assay methods
- PCR-based assays: general considerations and molecular underpinnings
- Commercially available tests
- General considerations for current molecular assays
- References
- Epidemiology of HHV6
- The epidemiology of roseola from historical observations
- Seroepidemiologic studies of HHV6 infection
- Acquisition of HHV6 infection during childhood
- Acquisition of HHV6 infection according to variant
- Factors affecting acquisition of HHV6 infection
- Mode of transmission
- Incubation period
- Summary
- References
- Part III: Clinical Pathology
- Pathologic Features of HHV-6 Disease
- Introduction
- Cell and tissue tropism and strain differences
- General cellular pathology of HHV-6 infection
- Primary infection
- Reactivation and endogenous reinfection
- Conclusions
- References
- Systemic Reactions to HHV &
