Viral Vectors for Treating Diseases of the Nervous System /

• Άλλοι συγγραφείς: Latchman, David S. (Επιμελητής έκδοσης)
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: San Diego, CA : Academic Press, 2003.
• Σειρά: International review of neurobiology ; v. 55.
• Θέματα: Genetic vectors.; Gene therapy.; Nervous system > Diseases > Gene therapy.; Adenoviruses.; Retroviruses.; Genetic Vectors.; Genetic Therapy.; Nervous System Diseases > therapy.; Adenoviridae.; Retroviridae.; Electronic books.

Gene therapy offers considerable potential for the treatment of various incurable diseases of the nervous system. This volume describes a number of different viral vectors developed for achieving high efficiency gene delivery to the brain. Vectors described include those based on adenovirus, adeno-a...

Πίνακας περιεχομένων:

• Section I. Virus vectors for use in the central nervous system. Nonneurotropic adenovirus: a vector for gene transfer to the brain and gene therapy of neurological disorders / Pedro R. Lowenstein [and others]. Adeno-associated viral vectors / E. Lehtonen and L. Tenenbaum. Problems in the use of herpes simplex virus as a vector / Lawrence T. Feldman. Lentiviral vectors / Johan Jakobsson [and others]. Retroviral vectors for gene delivery to neural precursor cells / Ryoichiro Kageyama, Hiromi Hirata, and Jun Hatakeyama
• Section II. Gene therapy with virus vectors for specific diseases of the nervous system. The principles of molecular therapies for glioblastoma / George Karpati and Josephine Nalbantoglu. Oncolytic herpes simplex virus for tumor therapy / Jennifer C.C. Hu and Robert S. Coffin. Recombinant retrovirus vectors for treatment of malignant brain tumors / Nikolai G. Rainov and Christof M. Kramm. Adeno-associated viral vectors for Parkinson's Disease / Shin-ichi Muramatsu [and others]. Herpes simplex virus vectors for Parkinson's Disease / David S. Latchman. Gene therapy for stroke / K. Abe and W.R. Zhang. Gene therapy for mucopolysaccharidosis / Assumpcio Bosch and Jean Michel Heard.