The Fly Neuromuscular Junction : Structure and Function /

• Other Authors: Budnik, Vivian (Editor), Ruiz-Cãnada, Catalina (Editor)
• Format: eBook
• Language: English
• Published: San Diego, CA : Elsevier/Academic Press, 2006.
• Edition: Second edition.
• Series: International review of neurobiology ; v. 75.
• Subjects: Drosophila melanogaster > Nervous system.; Fruit-flies > Nervous system.; Myoneural junction.; Drosophila melanogaster > Development.; Fruit-flies > Development.; Neuromuscular Junction.; Drosophila melanogaster.; NATURE > Animals > Insects & Spiders.; SCIENCE > Life Sciences > Zoology > Entomology.; Electronic books.
• Item Description: Revised edition of: Neuromuscular junctions in Drosophila / edited by Vivian Budnik and L. Sian Gramates. 1999.
• Physical Description: 1 online resource (xiv, 406 pages, 12 unnumbered leaves of plates) : illustrations (some color).
• Bibliography: Includes bibliographical references and index.
• ISBN: 9780080469133; 0080469132; 0123736137; 9780123736130

The Drosophila larval neuromuscular junction (NMJ) has become one of the most powerful model systems to ask key neurobiological questions. This synapse is unparalleled by its accessibility, its simplicity, and the ability to manipulate genes important for synapse development and function. Its synapses have properties shared by many organisms including humans. The vast majority of genes that when mutated cause congenital disorders of the nervous system in humans, are present in the fruit fly genome, and fly models of human disorders are available. Thus, this preparation is a powerful tool to u.