AID for Immunoglobulin Diversity /

Advances in Immunology, a long established and highly respected serial, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular ev...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Alt, Frederick W. (Επιμελητής έκδοσης), Honjo, T. (Tasuku), 1942- (Επιμελητής έκδοσης)
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Amsterdam ; Boston, Mass. : Academic Press, 2007.
Σειρά:Advances in immunology ; v. 94.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Discovery of Activation-Induced Cytidine Deaminase, the Engraver of Antibody Memory
  • DNA Deamination in Immunity: AID in the Context of Its APOBEC Relatives
  • The Role of Activation-Induced Deaminase in Antibody Diversification and Chromosome Translocations
  • Targeting of AID-Mediated Sequence Diversification by cis-Acting Determinants
  • AID-Initiated Purposeful Mutations in Immunoglobulin Genes
  • Evolution of the Immunoglobulin Heavy Chain Class Switch Recombination Mechanism
  • Beyond SHM and CSR: AID and Related Cytidine Deaminases in the Host Response to Viral Infection
  • Role of AID in Tumorigenesis
  • Pathophysiology of B-Cell Intrinsic Immunoglobulin Class Switch Recombination Deficiencies.